ethyl 5-amino-2-methyl-1,3-thiazole-4-carboxylate - Names and Identifiers
ethyl 5-amino-2-methyl-1,3-thiazole-4-carboxylate - Physico-chemical Properties
Molecular Formula | C7H10N2O2S
|
Molar Mass | 186.23 |
Density | 1.283±0.06 g/cm3(Predicted) |
Melting Point | 158-159 °C |
Boling Point | 301.9±22.0 °C(Predicted) |
Flash Point | 136.409°C |
Vapor Presure | 0.001mmHg at 25°C |
pKa | 2.38±0.10(Predicted) |
Storage Condition | 2-8°C(protect from light) |
Refractive Index | 1.579 |
ethyl 5-amino-2-methyl-1,3-thiazole-4-carboxylate - Risk and Safety
UN IDs | 1993 |
Hazard Class | 3 |
Packing Group | Ⅲ |
ethyl 5-amino-2-methyl-1,3-thiazole-4-carboxylate - Introduction
ethyl 5-amino-2-methyl-1,3-thiazole-4-carboxylate (also known as ethyl 5-amino-2-methyl-1,3-thiazole-4-carboxylate) is an organic compound with the chemical formula C7H10N2O2S.
Nature:
1. Appearance: ethyl 5-amino-2-methyl-1,3-thiazole-4-boxylate is a white or off-white crystalline solid.
2. Solubility: It is soluble in common organic solvents such as ethanol, dimethylformamide and dichloromethane.
3. Melting Point: its melting point is about 82-84 ° C.
Use:
ethyl 5-amino-2-methyl-1,3-thiazole-4-carboxylate has a wide range of applications in organic synthesis and is often used as an important intermediate. It can be used in the synthesis of biologically active compounds such as pharmaceuticals and pesticides.
Method:
The preparation of ethyl 5-amino-2-methyl-1,3-thiazole-4-carboxylate can be carried out by the following steps:
1. Get 2-methyl-4-carboxylic acid ethyl ester (also known as ethyl L).
2. By reducing 2-methyl -4-ethyl formate, 2-methyl -1,3-thiazole-4-ethyl formate (also known as ethyl L) is obtained.
3.2-methyl-1, 3-thiazole-4-carboxylic acid ethyl ester is reacted with ammonia to obtain ethyl 5-amino-2-methyl-1,3-thiazole-4-carboxylate.
Safety Information:
There is no clear information on the specific safety information and hazards of ethyl 5-amino-2-methyl-1,3-thiazole-4-boxylate. However, when contacting the compound, it is generally necessary to take care to prevent direct contact with the skin, eyes and respiratory tract, and to avoid inhalation or ingestion. Wear appropriate personal protective equipment such as gloves and goggles during use and operate in a well-ventilated area. If you accidentally touch or eat, you should seek medical attention immediately. When handling and storing, please follow the relevant safe operation and guidelines, and properly dispose of the waste of this compound.
Last Update:2024-04-09 21:54:55